Eastlake Rejuvenation Center - Topix/Eastlake Rejuvenation Center

More About CRS Rejuvenation Serum

About Vitamin C:

♦Vitamin C (L-Ascorbic Acid) is a powerful antioxidant that helps neutralize the damaging effects of free radicals- the unstable radicals that are a result of air pollution, smoking, stress and sunlight.
♦ Studies suggest that Vitamin C has the potential to stimulate the growth of collagen, which is important in maintaining healthy skin elasticity and texture.
♦ L-Ascorbic Acid is the chemical form of Ascorbic Acid that is most effectively utilized by the body. Ingredient Focus: TGF-beta-1 Growth Factor

A)Source of CRS TGF-b-1:

1) The TGF-beta-1 used in the CRS product line is produced by Recombinant DNA Technology (RDT)
2) It is a HUMAN Recombinant Protein, engineered by isolating the Human TGF genes in a test tube (similar to human recombinant insulin)
3) It is an ultra-pure compound with the same structure and efficacy as that found within the human body
4) It is NOT isolated from human tissue, nor a spent human cell culture medium, which abrogates possible concern over contamination with human factors or other agents.

B) Why We Chose TGF-b-1:TGF – Strengthens and rebuilds the dermal layer of the skin by:
1) Increasing the number of dermal cells (fibroblasts)
2) Stimulating the production of Extra-Cellular-Matrix materials, which:
a) firms the physical support structure of the skin
b) further hydrates, and therefore plumps-up’ the dermal layer
c) aids in the attachment of various other growth factors
d) provides overall proper (youthful) cellular functioning of the skin

TGF mainly targets the underlying dermal layer of the skin. Changes (thinning) to the dermal layer due to age and weathering are the cause of lines and wrinkles. TGF specifically helps repopulate the underlying dermal tissue with new cells. TGF directly causes the expression of various matrix compounds (collagens and proteoglycans) that both hydrate and regenerate the dermal structure, thereby decreasing lines and wrinkles.

C) Why not use additional growth factors in CRS:
1) Of the nearly one hundred identified cellular control factors of the skin, TGF-beta-1 has the broadest effects and controls the expression of a many other factors.
2) The interaction of various factors with each other and the various cells of the skin is highly complex; therefore, simply ‘dumping’ in factors is not a well considered treatment strategy, as it is likely to interfere with timing and coordination yielding less than optimal results.